PTPN2 (Human) Matched Antibody Pair
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More Files
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Sandwich ELISA detection sensitivity ranging from 1 ng/ml to 100 ng/ml.
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Specification
Product Description
This antibody pair set comes with a matched antibody pair to detect and quantify the protein level of human PTPN2.
Reactivity
Human
Quality Control Testing
Standard curve using recombinant protein ( H00005771-P01 ) as an analyte.
Sandwich ELISA detection sensitivity ranging from 1 ng/ml to 100 ng/ml.
Supplied Product
Antibody pair set content:
1. Capture antibody: rabbit MaxPab® affinity purified polyclonal anti-PTPN2 (100 ug)
2. Detection antibody: mouse purified polyclonal anti-PTPN2 (20 ug)
*Reagents are sufficient for at least 1-2 x 96 well plates using recommended protocols.Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
ELISA Pair (Recombinant protein)
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Gene Info — PTPN2
Entrez GeneID
5771Gene Name
PTPN2
Gene Alias
PTPT, TC-PTP, TCELLPTP, TCPTP
Gene Description
protein tyrosine phosphatase, non-receptor type 2
Omim ID
176887Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling. Three alternatively spliced variants of this gene, which encode isoforms differing at their extreme C-termini, have been described. The different C-termini are thought to determine the substrate specificity, as well as the cellular localization of the isoforms. Two highly related but distinctly processed pseudogenes that localize to distinct chromosomes have been reported. [provided by RefSeq
Other Designations
T-cell protein tyrosine phosphatase
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Interactome
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Disease
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