Western blot analysis of PTK9 over-expressed 293 cell line, cotransfected with PTK9 Validated Chimera RNAi ( Cat # H00005756-R01V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with PTK9 monoclonal antibody (M05) clone 1D12 (Cat # H00005756-M05 ). GAPDH ( 36.1 kDa ) used as specificity and loading control.
This gene encodes twinfilin, an actin monomer-binding protein conserved from yeast to mammals. Studies of the mouse counterpart suggest that this protein may be an actin monomer-binding protein, and its localization to cortical G-actin-rich structures may be regulated by the small GTPase RAC1. [provided by RefSeq
A6 protein tyrosine kinase,PTK9 protein tyrosine kinase 9,protein tyrosine kinase 9,twinfilin 1