PTK7 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human PTK7 partial ORF ( NP_002812, 36 a.a. - 145 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
KQPSSQDALQGRRALLRCEVEAPGPVHVYWLLDGAPVQDTERRFAQGSSLSFAAVDRLQDSGTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQ
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
37.84
Interspecies Antigen Sequence
Mouse (93)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — PTK7
Entrez GeneID
5754GeneBank Accession#
NM_002821Protein Accession#
NP_002812Gene Name
PTK7
Gene Alias
CCK4
Gene Description
PTK7 protein tyrosine kinase 7
Omim ID
601890Gene Ontology
HyperlinkGene Summary
Receptor protein tyrosine kinases transduce extracellular signals across the cell membrane. A subgroup of these kinases lack detectable catalytic tyrosine kinase activity but retain roles in signal transduction. The protein encoded by this gene is a member of this subgroup of tyrosine kinases and may function as a cell adhesion molecule. This gene is thought to be expressed in colon carcinomas but not in normal colon, and therefore may be a marker for or may be involved in tumor progression. Four transcript variants encoding four different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000039809|colon carcinoma kinase-4
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Interactome
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Publication Reference
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Binding-induced nicking site reconstruction strategy for quantitative detection of membrane protein on living cell.
Li W, Wang L, Wang Y, Jiang W.
Talanta 2018 Nov; 89:383.
Application：Func, Human, HeLa cells.
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A label-free sensitive method for membrane protein detection based on aptamer and AgNCs transfer.
Liu Z, Chen W, Han Y, Ouyang J, Chen M, Hu S, Deng L, Liu YN.
Talanta 2017 Jul; 175:470.
Application：Func, Human , CCRF-CEM, HeLa cells.
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Highly Sensitive and Homogeneous Detection of Membrane Protein on a Single Living Cell by Aptamer and Nicking Enzyme Assisted Signal Amplification Based on Microfluidic Droplets.
Li L, Wang Q, Feng J, Tong L, Tang B.
Analytical Chemistry 2014 May; 86(10):5101.
Application：Hairpin probe, Recombinant protein.
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Binding-induced nicking site reconstruction strategy for quantitative detection of membrane protein on living cell.
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