PTK7 monoclonal antibody (M04), clone 1A8
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant PTK7.
Immunogen
PTK7 (NP_002812, 36 a.a. ~ 145 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
KQPSSQDALQGRRALLRCEVEAPGPVHVYWLLDGAPVQDTERRFAQGSSLSFAAVDRLQDSGTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQ
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (93)
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.84 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
PTK7 monoclonal antibody (M04), clone 1A8 Western Blot analysis of PTK7 expression in HeLa ( Cat # L013V1 ).Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged PTK7 is approximately 3ng/ml as a capture antibody.ELISA
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Gene Info — PTK7
Entrez GeneID
5754GeneBank Accession#
NM_002821Protein Accession#
NP_002812Gene Name
PTK7
Gene Alias
CCK4
Gene Description
PTK7 protein tyrosine kinase 7
Omim ID
601890Gene Ontology
HyperlinkGene Summary
Receptor protein tyrosine kinases transduce extracellular signals across the cell membrane. A subgroup of these kinases lack detectable catalytic tyrosine kinase activity but retain roles in signal transduction. The protein encoded by this gene is a member of this subgroup of tyrosine kinases and may function as a cell adhesion molecule. This gene is thought to be expressed in colon carcinomas but not in normal colon, and therefore may be a marker for or may be involved in tumor progression. Four transcript variants encoding four different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000039809|colon carcinoma kinase-4
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