PTK2 monoclonal antibody (M03), clone 1D7
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More Files
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Western Blot (Cell lysate)
PTK2 monoclonal antibody (M03), clone 1D7. Western Blot analysis of PTK2 expression in Jurkat(Cat # L017V1 ).
Western Blot (Cell lysate)
PTK2 monoclonal antibody (M03), clone 1D7 Western Blot analysis of PTK2 expression in Hela S3 NE ( Cat # L013V3 ).
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged PTK2 is approximately 0.03ng/ml as a capture antibody.
Western Blot detection against Immunogen (40.59 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant PTK2.
Immunogen
PTK2 (AAH28733, 355 a.a. ~ 490 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
EGFYPSPQHMVQTNHYQVSGYPGSHGITAMAGSIYPGQASLLDQTDSWNHRPQEIAMWQPNVEDSTVLDLRGIGQVLPTHLMEERLIRQQQEMEEDQRWLEKEERFLKPDVRLSRGSIDREDGSLQGPIGNQHIYQ
Host
Mouse
Reactivity
Human
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (40.59 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
PTK2 monoclonal antibody (M03), clone 1D7. Western Blot analysis of PTK2 expression in Jurkat(Cat # L017V1 ).Western Blot (Cell lysate)
PTK2 monoclonal antibody (M03), clone 1D7 Western Blot analysis of PTK2 expression in Hela S3 NE ( Cat # L013V3 ).Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged PTK2 is approximately 0.03ng/ml as a capture antibody.ELISA
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Gene Info — PTK2
Entrez GeneID
5747GeneBank Accession#
BC028733Protein Accession#
AAH28733Gene Name
PTK2
Gene Alias
FADK, FAK, FAK1, pp125FAK
Gene Description
PTK2 protein tyrosine kinase 2
Omim ID
600758Gene Ontology
HyperlinkGene Summary
This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. At least four transcript variants encoding four different isoforms have been found for this gene, but the full-length natures of only two of them have been determined. [provided by RefSeq
Other Designations
focal adhesion kinase 1
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Interactome
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Pathway
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Disease
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