PTHLH DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human PTHLH DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MQRRLVQQWSVAVFLLSYAVPSCGRSVEGLSRRLKRAVSEHQLLHDKGKSIQDLRRRFFLHHLIAEIHTAEIRATSEVSPNSKPSPNTKNHPVRFGSDDEGRYLTQETNKVETYKEQPLKTPGKKKKGKPGKRKEQEKKKRRTRSAWLDSGVTGSGLEGDHLSDTSTTSLELDSRRH
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — PTHLH
Entrez GeneID
5744GeneBank Accession#
NM_198965.1Protein Accession#
NP_945316.1Gene Name
PTHLH
Gene Alias
HHM, MGC14611, PLP, PTHR, PTHRP
Gene Description
parathyroid hormone-like hormone
Omim ID
168470Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the parathyroid hormone family. This hormone regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. This hormone is involved in lactation possibly by regulating the mobilization and transfer of calcium to the milk. The receptor of this hormone, PTHR1, is responsible for most cases of humoral hypercalcemia of malignancy. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed. There is also evidence for alternative translation initiation from non-AUG (CUG and GUG) start sites, in-frame and downstream of the initiator AUG codon, to give rise to nuclear forms of this hormone. [provided by RefSeq
Other Designations
PTH-related protein|humoral hypercalcemia of malignancy|osteostatin|parathyroid hormone-like protein|parathyroid hormone-like related protein|parathyroid hormone-related protein|parathyroid-like protein
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Interactome
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Disease
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