PTHLH rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human PTHLH peptide using ARM Technology.
Immunogen
A synthetic peptide of human PTHLH is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human PTHLH peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — PTHLH
Entrez GeneID
5744GeneBank Accession#
PTHLHGene Name
PTHLH
Gene Alias
HHM, MGC14611, PLP, PTHR, PTHRP
Gene Description
parathyroid hormone-like hormone
Omim ID
168470Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the parathyroid hormone family. This hormone regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. This hormone is involved in lactation possibly by regulating the mobilization and transfer of calcium to the milk. The receptor of this hormone, PTHR1, is responsible for most cases of humoral hypercalcemia of malignancy. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed. There is also evidence for alternative translation initiation from non-AUG (CUG and GUG) start sites, in-frame and downstream of the initiator AUG codon, to give rise to nuclear forms of this hormone. [provided by RefSeq
Other Designations
PTH-related protein|humoral hypercalcemia of malignancy|osteostatin|parathyroid hormone-like protein|parathyroid hormone-like related protein|parathyroid hormone-related protein|parathyroid-like protein
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Interactome
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Disease
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