PTHLH purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human PTHLH protein.
Immunogen
PTHLH (NP_945316.1, 1 a.a. ~ 177 a.a) full-length human protein.
Sequence
MQRRLVQQWSVAVFLLSYAVPSCGRSVEGLSRRLKRAVSEHQLLHDKGKSIQDLRRRFFLHHLIAEIHTAEIRATSEVSPNSKPSPNTKNHPVRFGSDDEGRYLTQETNKVETYKEQPLKTPGKKKKGKPGKRKEQEKKKRRTRSAWLDSGVTGSGLEGDHLSDTSTTSLELDSRRH
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of PTHLH expression in transfected 293T cell line (H00005744-T01) by PTHLH MaxPab polyclonal antibody.
Lane 1: PTHLH transfected lysate(19.47 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to PTHLH on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — PTHLH
Entrez GeneID
5744GeneBank Accession#
NM_198965Protein Accession#
NP_945316.1Gene Name
PTHLH
Gene Alias
HHM, MGC14611, PLP, PTHR, PTHRP
Gene Description
parathyroid hormone-like hormone
Omim ID
168470Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the parathyroid hormone family. This hormone regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. This hormone is involved in lactation possibly by regulating the mobilization and transfer of calcium to the milk. The receptor of this hormone, PTHR1, is responsible for most cases of humoral hypercalcemia of malignancy. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed. There is also evidence for alternative translation initiation from non-AUG (CUG and GUG) start sites, in-frame and downstream of the initiator AUG codon, to give rise to nuclear forms of this hormone. [provided by RefSeq
Other Designations
PTH-related protein|humoral hypercalcemia of malignancy|osteostatin|parathyroid hormone-like protein|parathyroid hormone-like related protein|parathyroid hormone-related protein|parathyroid-like protein
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Interactome
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Disease
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