PTGS1 MaxPab rabbit polyclonal antibody (D01)
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More Files
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Western Blot (Tissue lysate)
PTGS1 MaxPab rabbit polyclonal antibody. Western Blot analysis of PTGS1 expression in mouse spleen.
Western Blot (Cell lysate)
PTGS1 MaxPab rabbit polyclonal antibody. Western Blot analysis of PTGS1 expression in HeLa.
Western Blot (Transfected lysate)
Western Blot analysis of PTGS1 expression in transfected 293T cell line (H00005742-T01) by PTGS1 MaxPab polyclonal antibody.
Lane 1: PTGS1 transfected lysate(68.70 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of PTGS1 transfected lysate using anti-PTGS1 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with PTGS1 purified MaxPab mouse polyclonal antibody (B01P) (H00005742-B01P).
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human PTGS1 protein.
Immunogen
PTGS1 (AAH29840.1, 1 a.a. ~ 599 a.a) full-length human protein.
Sequence
MSRSLLLRFLLFLLLLPPLPVLLADPGAPTPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYSGPNCTIPGLWTWLRNSLRPSPSFTHFLLTHGRWFWEFVNATFIREMLMRLVLTVRSNLIPSPPTYNSAHDYISWESFSNVSYYTRILPSVPKDCPTPMGTKGKKQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRIAMEFNHLYHWHPLMPDSFKVGSQEYSYEQFLFNTSMLVDYGVEALVDAFSRQIAGRIGGGRNMDHHILHVAVDVIRESREMRLQPFNEYRKRFGMKPYTSFQELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEIGAPFSLKGLLGNPICSPEYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSFRVPDASQDDGPAVERPSTEL
Host
Rabbit
Reactivity
Human, Mouse
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
PTGS1 MaxPab rabbit polyclonal antibody. Western Blot analysis of PTGS1 expression in mouse spleen.Western Blot (Cell lysate)
PTGS1 MaxPab rabbit polyclonal antibody. Western Blot analysis of PTGS1 expression in HeLa.Western Blot (Transfected lysate)
Western Blot analysis of PTGS1 expression in transfected 293T cell line (H00005742-T01) by PTGS1 MaxPab polyclonal antibody.
Lane 1: PTGS1 transfected lysate(68.70 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of PTGS1 transfected lysate using anti-PTGS1 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with PTGS1 purified MaxPab mouse polyclonal antibody (B01P) (H00005742-B01P). -
Gene Info — PTGS1
Entrez GeneID
5742GeneBank Accession#
BC029840.1Protein Accession#
AAH29840.1Gene Name
PTGS1
Gene Alias
COX1, COX3, PCOX1, PGG/HS, PGHS-1, PGHS1, PHS1, PTGHS
Gene Description
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
Omim ID
176805Gene Ontology
HyperlinkGene Summary
Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes PTGS1, which regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. PTGS1 is thought to be involved in cell-cell signaling and maintaining tissue homeostasis. Alternative splicing of this gene generates two transcript variants. The expression of these two transcripts is differentially regulated by relevant cytokines and growth factors. [provided by RefSeq
Other Designations
OTTHUMP00000022052|OTTHUMP00000022053|prostaglandin G/H synthase and cyclooxygenase|prostaglandin-endoperoxide synthase 1
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Interactome
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Pathway
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Disease
- Abdominal Pain
- Adenocarcinoma
- Adenoma
- Adenomatous Polyps
- Alzheimer disease
- Asthma
- Atherosclerosis
- Atrophy
- Brain Ischemia
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