PTGIS (Human) IP-WB Antibody Pair
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of PTGIS transfected lysate using rabbit polyclonal anti-PTGIS and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-PTGIS.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: rabbit polyclonal anti-PTGIS (300 ul)
2. Antibody pair for WB: mouse purified polyclonal anti-PTGIS (50 ug)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — PTGIS
Entrez GeneID
5740Gene Name
PTGIS
Gene Alias
CYP8, CYP8A1, MGC126858, MGC126860, PGIS, PTGI
Gene Description
prostaglandin I2 (prostacyclin) synthase
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction, stroke, and atherosclerosis. [provided by RefSeq
Other Designations
OTTHUMP00000031777|cytochrome P450, family 8, subfamily A, polypeptide 1
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