PTGIR monoclonal antibody (M02), clone 2A7
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant PTGIR.
Immunogen
PTGIR (NP_000951, 296 a.a. ~ 386 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
RKAVFQRLKLWVCCLCLGPAHGDSQTPLSQLASGRRDPRAPSAPVGKEGSCVPLSAWGEGQVEPLPPTQQSSGSAVGTSSKAEASVACSLC
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (62); Rat (61)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (35.75 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of PTGIR expression in transfected 293T cell line by PTGIR monoclonal antibody (M02), clone 2A7.
Lane 1: PTGIR transfected lysate(41 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged PTGIR is approximately 0.1ng/ml as a capture antibody.ELISA
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Gene Info — PTGIR
Entrez GeneID
5739GeneBank Accession#
NM_000960Protein Accession#
NP_000951Gene Name
PTGIR
Gene Alias
IP, MGC102830, PRIPR
Gene Description
prostaglandin I2 (prostacyclin) receptor (IP)
Omim ID
600022Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the G-protein coupled receptor family 1 and has been shown to be a receptor for prostacyclin. Prostacyclin, the major product of cyclooxygenase in macrovascular endothelium, elicits a potent vasodilation and inhibition of platelet aggregation through binding to this receptor. [provided by RefSeq
Other Designations
PGI receptor|prostacyclin receptor|prostanoid IP receptor
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Interactome
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Pathway
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Disease
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