PTGFR (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human PTGFR full-length ORF ( NP_000950.1, 1 a.a. - 359 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MSMNNSKQLVSPAAALLSNTTCQTENRLSVFFSVIFMTVGILSNSLAIAILMKAYQRFRQKSKASFLLLASGLVITDFFGHLINGAIAVFVYASDKEWIRFDQSNVLCSIFGICMVFSGLCPLLLGSVMAIERCIGVTKPIFHSTKITSKHVKMMLSGVCLFAVFIALLPILGHRDYKIQASRTWCFYNTEDIKDWEDRFYLLLFSFLGLLALGVSLLCNAITGITLLRVKFKSQQHRQGRSHHLEMVIQLLAIMCVSCICWSPFLVTMANIGINGNHSLETCETTLFALRMATWNQILDPWVYILLRKAVLKNLYKLASQCCGVHVISLHIWELSSIKNSLKVAAISESPVAEKSAST
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
66.5
Interspecies Antigen Sequence
Mouse (89); Rat (88)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — PTGFR
Entrez GeneID
5737GeneBank Accession#
NM_000959.3Protein Accession#
NP_000950.1Gene Name
PTGFR
Gene Alias
FP, MGC120498, MGC46203
Gene Description
prostaglandin F receptor (FP)
Omim ID
600563Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is member of the G-protein coupled receptor family. This protein is a receptor for prostaglandin F2-alpha (PGF2-alpha), which is known to be a potent luteolytic agent, and may also be involved in modulating intraocular pressure and smooth muscle contraction in uterus. Knockout studies in mice suggest that the interaction of PGF2-alpha with this receptor may initiate parturition in ovarian luteal cells and thus induce luteolysis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000011218|OTTHUMP00000011219|OTTHUMP00000037508|PGF receptor|PGF2 alpha receptor|prostaglandin F receptor|prostaglandin F2 alpha receptor|prostaglandin receptor (2-alpha)|prostanoid FP receptor
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Interactome
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Pathway
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Disease
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