PTGFR rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human PTGFR peptide using ARM Technology.
Immunogen
A synthetic peptide of human PTGFR is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human PTGFR peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — PTGFR
Entrez GeneID
5737GeneBank Accession#
PTGFRGene Name
PTGFR
Gene Alias
FP, MGC120498, MGC46203
Gene Description
prostaglandin F receptor (FP)
Omim ID
600563Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is member of the G-protein coupled receptor family. This protein is a receptor for prostaglandin F2-alpha (PGF2-alpha), which is known to be a potent luteolytic agent, and may also be involved in modulating intraocular pressure and smooth muscle contraction in uterus. Knockout studies in mice suggest that the interaction of PGF2-alpha with this receptor may initiate parturition in ovarian luteal cells and thus induce luteolysis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000011218|OTTHUMP00000011219|OTTHUMP00000037508|PGF receptor|PGF2 alpha receptor|prostaglandin F receptor|prostaglandin F2 alpha receptor|prostaglandin receptor (2-alpha)|prostanoid FP receptor
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