PTGER3 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human PTGER3 peptide using ARM Technology.
Immunogen
A synthetic peptide of human PTGER3 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human PTGER3 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — PTGER3
Entrez GeneID
5733GeneBank Accession#
PTGER3Gene Name
PTGER3
Gene Alias
EP3, EP3-I, EP3-II, EP3-III, EP3-IV, EP3e, MGC141828, MGC141829, MGC27302
Gene Description
prostaglandin E receptor 3 (subtype EP3)
Omim ID
176806Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor may have many biological functions, which involve digestion, nervous system, kidney reabsorption, and uterine contraction activities. Studies of the mouse counterpart suggest that this receptor may also mediate adrenocorticotropic hormone response as well as fever generation in response to exogenous and endogenous stimuli. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000011033|OTTHUMP00000011034|OTTHUMP00000011035|PGE receptor, EP3 subtype|prostaglandin E receotor EP3 subtype 3 isoform|prostaglandin E receptor 3, subtype EP3|prostaglandin E2 receptor|prostaglandin receptor (PGE-2)|prostanoid EP3 receptor
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