PTGER1 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human PTGER1 full-length ORF ( NP_000946.2, 1 a.a. - 402 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MSPCGPLNLSLAGEATTCAAPWVPNTSAVPPSGASPALPIFSMTLGAVSNLLALALLAQAAGRLRRRRSAATFLLFVASLLATDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTRPLLHAARVSVARARLALAAVAAVALAVALLPLARVGRYELQYPGTWCFIGLGPPGGWRQALLAGLFASLGLVALLAALVCNTLSGLALLRARWRRRSRRPPPASGPDSRRRWGAHGPRSASASSASSIASASTFFGGSRSSGSARRARAHDVEMVGQLVGIMVVSCICWSPMLVLVALAVGGWSSTSLQRPLFLAVRLASWNQILDPWVYILLRQAVLRQLLRLLPPRAGAKGGPAGLGLTPSAWEASSLRSSRHSGLSHF
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
68.2
Interspecies Antigen Sequence
Mouse (83); Rat (83)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — PTGER1
Entrez GeneID
5731GeneBank Accession#
NM_000955.2Protein Accession#
NP_000946.2Gene Name
PTGER1
Gene Alias
EP1
Gene Description
prostaglandin E receptor 1 (subtype EP1), 42kDa
Omim ID
176802Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the G protein-coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). Through a phosphatidylinositol-calcium second messenger system, G-Q proteins mediate this receptor's activity. Knockout studies in mice suggested a role of this receptor in mediating algesia and in regulation of blood pressure. Studies in mice also suggested that this gene may mediate adrenocorticotropic hormone response to bacterial endotoxin. [provided by RefSeq
Other Designations
PGE receptor, EP1 subtype|prostaglandin E receptor 1, subtype EP1|prostanoid EP1 receptor
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Interactome
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Pathway
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Disease
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