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PTGDS rabbit monoclonal antibody

  • Catalog # : H00005730-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human PTGDS peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human PTGDS is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human PTGDS peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 5730
  • GeneBank Accession#:
  • PTGDS
  • Gene Name:
  • PTGDS
  • Gene Alias:
  • LPGDS,PDS,PGD2,PGDS,PGDS2
  • Gene Description:
  • prostaglandin D2 synthase 21kDa (brain)
  • Gene Summary:
  • The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This gene is preferentially expressed in brain. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement sleep. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000022638,PGD2 synthase,beta-trace protein,glutathione-independent PGD synthase,lipocalin-type prostaglandin D synthase,prostaglandin D synthase,prostaglandin D2 synthase (21kD, brain),prostaglandin H2 D-isomerase,prostaglandin-H2 D-isomerase
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