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PTCH Pre-design Chimera RNAi

  • Catalog # : H00005727-R02
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens patched homolog (Drosophila) (PTCH), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_000264
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 5727
  • Gene Name:
  • PTCH1
  • Gene Alias:
  • BCNS,FLJ26746,FLJ42602,HPE7,NBCCS,PTC,PTC1,PTCH,PTCH11
  • Gene Description:
  • patched homolog 1 (Drosophila)
  • Gene Summary:
  • This gene encodes a member of the patched gene family. The encoded protein is the receptor for sonic hedgehog, a secreted molecule implicated in the formation of embryonic structures and in tumorigenesis, as well as the desert hedgehog and indian hedgehog proteins. This gene functions as a tumor suppressor. Mutations of this gene have been associated with basal cell nevus syndrome, esophageal squamous cell carcinoma, trichoepitheliomas, transitional cell carcinomas of the bladder, as well as holoprosencephaly. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences and biological validity cannot be determined currently. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000021709,OTTHUMP00000021710,PTCH protein +12b,PTCH protein +4',PTCH protein -10,patched
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