PSMD13 purified MaxPab mouse polyclonal antibody (B03P)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human PSMD13 protein.
Immunogen
PSMD13 (NP_002808.2, 1 a.a. ~ 376 a.a) full-length human protein.
Sequence
MKDVPGFLQQSQSSGPGQPAVWHRLEELYTKKLWHQLTLQVLDFVQDPCFAQGDGLIKLYENFISEFEHRVNPLSLVEIILHVVRQMTDPNVALTFLEKTREKVKSSDEAVILCKTAIGALKLNIGDLQVTKETIEDVEEMLNNLPGVTSVHSRFYDLSSKYYQTIGNHASYYKDALRFLGCVDIKDLPVSEQQERAFTLGLAGLLGEGVFNFGELLMHPVLESLRNTDRQWLIDTLYAFNSGNVERFQTLKTAWGQQPDLAANEAQLLRKIQLLCLMEMTFTRPANHRQLTFEEIAKSAKITVNEVELLVMKALSVGLVKGSIDEVDKRVHMTWVQPRVLDLQQIKGMKDRLEFWCTDVKSMEMLVEHQAHDILT
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (97); Rat (97)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of PSMD13 expression in transfected 293T cell line (H00005719-T05) by PSMD13 MaxPab polyclonal antibody.
Lane 1: PSMD13 transfected lysate(42.90 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — PSMD13
Entrez GeneID
5719GeneBank Accession#
NM_002817Protein Accession#
NP_002808.2Gene Name
PSMD13
Gene Alias
HSPC027, Rpn9, S11, p40.5
Gene Description
proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
Omim ID
603481Gene Ontology
HyperlinkGene Summary
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Two transcripts encoding different isoforms have been described. [provided by RefSeq
Other Designations
26S proteasome regulatory subunit S11|26S proteasome subunit p40.5|proteasome 26S non-ATPase subunit 13
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Interactome
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Pathway
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