PSMD13 purified MaxPab mouse polyclonal antibody (B02P)
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human PSMD13 protein.
Immunogen
PSMD13 (NP_002808, 1 a.a. ~ 376 a.a) full-length human protein.
Sequence
MKDVPGFLQQSQSSGPGQPAVWHRLEELYTKKLWHQLTLQVLDFVQDPCFAQGDGLIKLYENFISEFEHRVNPLSLVEIILHVVRQMTDPNVALTFLEKTREKVKSSDEAVILCKTAIGALKLNIGDLQVTKETIEDVEEMLNNLPGVTSVHSRFYDLSSKYYQTIGNHASYYKDALRFLGCVDIKDLPVSEQQERAFTLGLAGLLGEGVFNFGELLMHPVLESLRNTDRQWLIDTLYAFNSGNVERFQTLKTAWGQQPDLAANEAQLLRKIQLLCLMEMTFTRPANHRQLTFEEIAKSAKITVNEVELLVMKALSVGLVKGSIDEVDKRVHMTWVQPRVLDLQQIKGMKDRLEFWCTDVKSMEMLVEHQAHDILT
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (97); Rat (97)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
PSMD13 MaxPab polyclonal antibody. Western Blot analysis of PSMD13 expression in human liver.Western Blot (Cell lysate)
PSMD13 MaxPab polyclonal antibody. Western Blot analysis of PSMD13 expression in HeLa.Western Blot (Transfected lysate)
Western Blot analysis of PSMD13 expression in transfected 293T cell line (H00005719-T04) by PSMD13 MaxPab polyclonal antibody.
Lane 1: PSMD13 transfected lysate(41.36 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — PSMD13
Entrez GeneID
5719GeneBank Accession#
NM_002817Protein Accession#
NP_002808Gene Name
PSMD13
Gene Alias
HSPC027, Rpn9, S11, p40.5
Gene Description
proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
Omim ID
603481Gene Ontology
HyperlinkGene Summary
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Two transcripts encoding different isoforms have been described. [provided by RefSeq
Other Designations
26S proteasome regulatory subunit S11|26S proteasome subunit p40.5|proteasome 26S non-ATPase subunit 13
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Interactome
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Pathway
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