PSMD4 (Human) Matched Antibody Pair
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Specification
Product Description
This antibody pair set comes with a matched antibody pair to detect and quantify the protein level of human PSMD4.
Reactivity
Human
Quality Control Testing
Standard curve using PSMD4 293T overexpression lysate (non-denatured) as an analyte.
Sandwich ELISA detection sensitivity ranging from approximately 2187x to 3x dilution of the PSMD4 293T overexpression lysate (non-denatured).
Supplied Product
Antibody pair set content:
1. Capture antibody: rabbit MaxPab® affinity purified polyclonal anti-PSMD4 (100 ug)
2. Detection antibody: mouse monoclonal anti-PSMD4, IgG2a Kappa (20 ug)
*Reagents are sufficient for at least 1-2 x 96 well plates using recommended protocols.Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
ELISA Pair (Transfected lysate)
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Gene Info — PSMD4
Entrez GeneID
5710Gene Name
PSMD4
Gene Alias
AF, AF-1, ASF, MCB1, Rpn10, S5A, pUB-R5
Gene Description
proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
Omim ID
601648Gene Ontology
HyperlinkGene Summary
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid. Pseudogenes have been identified on chromosomes 10 and 21. [provided by RefSeq
Other Designations
26S protease subunit S5a|26S proteasome non-ATPase regulatory subunit 4|OTTHUMP00000014286|OTTHUMP00000059963|S5a/antisecretory factor protein|angiocidin|antisecretory factor 1|multiubiquitin chain binding protein|proteasome 26S non-ATPase subunit 4
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Interactome
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Pathway
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