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PSMD2 Pre-design Chimera RNAi

  • Catalog # : H00005708-R01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 (PSMD2), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_002808
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 5708
  • Gene Name:
  • PSMD2
  • Gene Alias:
  • MGC14274,P97,Rpn1,S2,TRAP2
  • Gene Description:
  • proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
  • Gene Summary:
  • The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid. In addition to participation in proteasome function, this subunit may also participate in the TNF signalling pathway since it interacts with the tumor necrosis factor type 1 receptor. A pseudogene has been identified on chromosome 1. [provided by RefSeq
  • Other Designations:
  • 26S proteasome non-ATPase regulatory subunit 2,26S proteasome regulatory subunit S2,26S proteasome subunit p97,55.11 protein,TNFR-associated protein 2,proteasome 26S non-ATPase subunit 2,tumor necrosis factor receptor-associated protein 2
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