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PSMD1 Pre-design Chimera RNAi

  • Catalog # : H00005707-R01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 (PSMD1), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_002807
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 5707
  • Gene Name:
  • PSMD1
  • Gene Alias:
  • MGC133040,MGC133041,P112,Rpn2,S1
  • Gene Description:
  • proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
  • Gene Summary:
  • The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes the largest non-ATPase subunit of the 19S regulator lid, which is responsible for substrate recognition and binding. [provided by RefSeq
  • Other Designations:
  • 26S proteasome non-ATPase regulatory subunit 1,26S proteasome regulatory subunit S1,26S proteasome subunit p112,proteasome 26S non-ATPase subunit 1
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