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Last updated: 2016/10/16
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PSMC3 purified MaxPab mouse polyclonal antibody (B01P)MaxPab

  • Catalog # : H00005702-B01P
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  • Specification
  • Product Description:
  • Mouse polyclonal antibody raised against a full-length human PSMC3 protein.
  • Immunogen:
  • PSMC3 (NP_002795.2, 1 a.a. ~ 439 a.a) full-length human protein.
  • Sequence:
  • Host:
  • Mouse
  • Reactivity:
  • Human, Rat
  • Quality Control Testing:
  • Antibody reactive against mammalian transfected lysate.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • PSMC3 MaxPab polyclonal antibody. Western Blot analysis of PSMC3 expression in rat brain.
  • PDF DownloadProtocol Download
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western Blot analysis of PSMC3 expression in transfected 293T cell line (H00005702-T01) by PSMC3 MaxPab polyclonal antibody.

    Lane 1: PSMC3 transfected lysate(48.29 KDa).
    Lane 2: Non-transfected lysate.
  • PDF DownloadProtocol Download
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 5702
  • Gene Name:
  • PSMC3
  • Gene Alias:
  • MGC8487,TBP1
  • Gene Description:
  • proteasome (prosome, macropain) 26S subunit, ATPase, 3
  • Gene Summary:
  • The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases that have chaperone-like activity. This subunit may compete with PSMC2 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex. A pseudogene has been identified on chromosome 9. [provided by RefSeq
  • Other Designations:
  • Tat-binding protein 1,human immunodeficiency virus tat transactivator binding protein-1,proteasome 26S ATPase subunit 3,proteasome subunit P50
  • Gene Pathway
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