PSMB4 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human PSMB4 full-length ORF ( AAH00331, 1 a.a. - 264 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MEAFLGSRSGLWAGGPAPGQFYRIPSTPDSFMDPASALYRGPITRTQNPMVTGTSVLGVKFEGGVVIAADMLGSYGSLARFRNISRIMRVNNSTMLGASGDYADFQYLKQVLGQMVIDEELLGDGHSYSPRAIHSWLTRAMYSRRSKMNPLWNTMVIGGYADGESFLGYVDMLGVAYEAPSLATGYGAYLAQPLLREVLEKQPVLSQTEARDLVERCMRVLYYRDARSYNRFQTATVTEKGVEIEGPLSTETNWDIAHMISGFE
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
54.78
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — PSMB4
Entrez GeneID
5692GeneBank Accession#
BC000331Protein Accession#
AAH00331Gene Name
PSMB4
Gene Alias
HN3, HsN3, PROS26
Gene Description
proteasome (prosome, macropain) subunit, beta type, 4
Omim ID
602177Gene Ontology
HyperlinkGene Summary
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. [provided by RefSeq
Other Designations
macropain beta chain|multicatalytic endopeptidase complex beta chain|proteasome beta 4 subunit|proteasome beta chain|proteasome chain 3|proteasome subunit HsN3|proteasome subunit, beta type, 4
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Interactome
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Pathway
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Disease
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