PSMB1 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human PSMB1 full-length ORF ( NP_002784.1, 1 a.a. - 241 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MLSSTAMYSAPGRDLGMEPHRAAGPLQLRFSPYVFNGGTILAIAGEDFAIVASDTRLSEGFSIHTRDSPKCYKLTDKTVIGCSGFHGDCLTLTKIIEARLKMYKHSNNKAMTTGAIAAMLSTILYSRRFFPYYVYNIIGGLDEEGKGAVYSFDPVGSYQRDSFKAGGSASAMLQPLLDNQVGFKNMQNVEHVPLSLDRAMRLVKDVFISAAERDVYTGDALRICIVTKEGIREETVSLRKD
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
52.9
Interspecies Antigen Sequence
Mouse (94); Rat (92)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — PSMB1
Entrez GeneID
5689GeneBank Accession#
NM_002793.2Protein Accession#
NP_002784.1Gene Name
PSMB1
Gene Alias
FLJ25321, HC5, KIAA1838, PMSB1, PSC5
Gene Description
proteasome (prosome, macropain) subunit, beta type, 1
Omim ID
602017Gene Ontology
HyperlinkGene Summary
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is tightly linked to the TBP (TATA-binding protein) gene in human and in mouse, and is transcribed in the opposite orientation in both species. [provided by RefSeq
Other Designations
macropain subunit C5|multicatalytic endopeptidase complex subunit C5|proteasome beta 1 subunit|proteasome component C5|proteasome gamma chain|proteasome subunit HC5
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Interactome
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Pathway
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Disease
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