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PSMA7 (Human) IP-WB Antibody Pair

  • Catalog # : H00005688-PW2
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  • Specification
  • Product Description:
  • This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Immunoprecipitation-Western Blot (IP-WB)

    QC Testing of H00005688-PW2
    Immunoprecipitation of PSMA7 transfected lysate using rabbit polyclonal anti-PSMA7 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse polyclonal anti-PSMA7.
  • Supplied Product:
  • Antibody pair set content:
    1. Antibody pair for IP: rabbit polyclonal anti-PSMA7 (300 ul)
    2. Antibody pair for WB: mouse polyclonal anti-PSMA7 (50 ul)
  • Storage Instruction:
  • Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
  • Applications
  • Application Image
  • Immunoprecipitation-Western Blot
  • Gene Information
  • Entrez GeneID:
  • 5688
  • Gene Name:
  • PSMA7
  • Gene Alias:
  • C6,HSPC,MGC3755,RC6-1,XAPC7
  • Gene Description:
  • proteasome (prosome, macropain) subunit, alpha type, 7
  • Gene Summary:
  • The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. This particular subunit has been shown to interact specifically with the hepatitis B virus X protein, a protein critical to viral replication. In addition, this subunit is involved in regulating hepatitis virus C internal ribosome entry site (IRES) activity, an activity essential for viral replication. This core alpha subunit is also involved in regulating the hypoxia-inducible factor-1alpha, a transcription factor important for cellular responses to oxygen tension. Multiple isoforms of this subunit arising from alternative splicing may exist but alternative transcripts for only two isoforms have been defined. A pseudogene has been identified on chromosome 9. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000031449,proteasome alpha 7 subunit,proteasome subunit RC6-1,proteasome subunit XAPC7,proteasome subunit alpha 4
  • Gene Pathway
  • Related Disease
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