Products

Enzyme-linked Immunoabsorbent Assay

Western Blot (Recombinant protein)

Antibody Production

Protein Array

Entrez GeneID

GeneBank Accession#

Protein Accession#

Gene Name

PSMA4

Gene Alias

HC9, HsT17706, MGC111191, MGC12467, MGC24813, PSC9

Gene Description

proteasome (prosome, macropain) subunit, alpha type, 4

Omim ID

Gene Ontology

Gene Summary

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

Other Designations

macropain subunit C9|multicatalytic endopeptidase complex subunit C9|proteasome alpha 4 subunit|proteasome component C9|proteasome subunit HC9|proteasome subunit L