KLK10 monoclonal antibody (M02), clone 1B9
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant KLK10.
Immunogen
KLK10 (NP_002767, 167 a.a. ~ 276 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
DQCQVAGWGTTAARRVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAGLDRGQDPCQSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQICKYMSWINKVIRSN
Host
Mouse
Reactivity
Human
Isotype
IgG1 Lambda
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.84 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged KLK10 is approximately 1ng/ml as a capture antibody.ELISA
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Gene Info — KLK10
Entrez GeneID
5655GeneBank Accession#
NM_002776Protein Accession#
NP_002767Gene Name
KLK10
Gene Alias
NES1, PRSSL1
Gene Description
kallikrein-related peptidase 10
Omim ID
602673Gene Ontology
HyperlinkGene Summary
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein. [provided by RefSeq
Other Designations
breast normal epithelial cell associated serine protease|kallikrein 10|normal epithelial cell-specific 1|protease, serine-like, 1
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Interactome
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Disease
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