PRSS7 monoclonal antibody (M01), clone 3F8
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant PRSS7.
Immunogen
PRSS7 (NP_002763, 361 a.a. ~ 470 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
NDDNEWERIQGSTFSPFTGPNFDHTFGNASGFYISTPTGPGGRQERVGLLSLPLDPTLEPACLSFWYHMYGENVHKLSINISNDQNMEKTVFQKEGNYGDNWNYGQVTLN
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (67); Rat (61)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.84 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged PRSS7 is approximately 0.03ng/ml as a capture antibody.ELISA
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Gene Info — PRSS7
Entrez GeneID
5651GeneBank Accession#
NM_002772Protein Accession#
NP_002763Gene Name
PRSS7
Gene Alias
ENTK, MGC133046
Gene Description
protease, serine, 7 (enterokinase)
Gene Ontology
HyperlinkGene Summary
This gene encodes an enzyme that converts the pancreatic proenzyme trypsinogen to trypsin, which activates other proenzymes including chymotrypsinogen and procarboxypeptidases. The precursor protein is cleaved into two chains that form a heterodimer linked by a disulfide bond. This protein is a member of the trypsin family of peptidases. Mutations in this gene cause enterokinase deficiency, a malabsorption disorder characterized by diarrhea and failure to thrive. [provided by RefSeq
Other Designations
enterokinase|enteropeptidase|proenterokinase, enteropeptidase, serine protease|serine protease
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Interactome
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Disease
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