Products

Western Blot (Transfected lysate)

Immunofluorescence (Transfected cell)

Flow Cytometry (Transfected cell)

Entrez GeneID

GeneBank Accession#

Protein Accession#

Gene Name

MASP1

Gene Alias

CRARF, CRARF1, DKFZp686I01199, FLJ26383, MASP, MGC126283, MGC126284, PRSS5, RaRF

Gene Description

mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)

Omim ID

Gene Ontology

Gene Summary

The Ra-reactive factor (RARF) is a complement-dependent bactericidal factor that binds to the Ra and R2 polysaccharides expressed by certain enterobacteria. Alternate splicing of this gene results in multiple transcript variants encoding two RARF components that are involved in the mannan-binding lectin (MBL) pathway of complement activation. Two of the isoforms are cleaved into two chains which form a heterodimer linked by a disulfide bond. The encoded proteins are members of the trypsin family of peptidases. [provided by RefSeq

Other Designations

Ra-reactive factor serine protease p100|manan-binding lectin serine protease-1|mannan-binding lectin serine protease 1|mannan-binding lectin serine protease 1 (C4/C2 activating component of Ra-reactive factor)|mannan-binding lectin serine protease 1, isof