MASP1 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human MASP1 full-length ORF ( NP_001027019.1, 1 a.a. - 380 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MRWLLLYYALCFSLSKASAHTVELNNMFGQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYFMHFNLESSYLCEYDYVKVETEDQVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHYMAVDVDECKEREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRTCRVECSDNLFTQRTGVITSPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEVPCPYDYIKIKVGPKVLGPFCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSYRAAGNECPELQPPVHGKIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNKIPTCKKNEIDLESELKSEQVTE
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
70
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — MASP1
Entrez GeneID
5648GeneBank Accession#
NM_001031849.1Protein Accession#
NP_001027019.1Gene Name
MASP1
Gene Alias
CRARF, CRARF1, DKFZp686I01199, FLJ26383, MASP, MGC126283, MGC126284, PRSS5, RaRF
Gene Description
mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
Omim ID
600521Gene Ontology
HyperlinkGene Summary
The Ra-reactive factor (RARF) is a complement-dependent bactericidal factor that binds to the Ra and R2 polysaccharides expressed by certain enterobacteria. Alternate splicing of this gene results in multiple transcript variants encoding two RARF components that are involved in the mannan-binding lectin (MBL) pathway of complement activation. Two of the isoforms are cleaved into two chains which form a heterodimer linked by a disulfide bond. The encoded proteins are members of the trypsin family of peptidases. [provided by RefSeq
Other Designations
Ra-reactive factor serine protease p100|manan-binding lectin serine protease-1|mannan-binding lectin serine protease 1|mannan-binding lectin serine protease 1 (C4/C2 activating component of Ra-reactive factor)|mannan-binding lectin serine protease 1, isof
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Interactome
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Pathway
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Disease
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