MASP1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human MASP1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human MASP1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human MASP1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — MASP1
Entrez GeneID
5648GeneBank Accession#
MASP1Gene Name
MASP1
Gene Alias
CRARF, CRARF1, DKFZp686I01199, FLJ26383, MASP, MGC126283, MGC126284, PRSS5, RaRF
Gene Description
mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
Omim ID
600521Gene Ontology
HyperlinkGene Summary
The Ra-reactive factor (RARF) is a complement-dependent bactericidal factor that binds to the Ra and R2 polysaccharides expressed by certain enterobacteria. Alternate splicing of this gene results in multiple transcript variants encoding two RARF components that are involved in the mannan-binding lectin (MBL) pathway of complement activation. Two of the isoforms are cleaved into two chains which form a heterodimer linked by a disulfide bond. The encoded proteins are members of the trypsin family of peptidases. [provided by RefSeq
Other Designations
Ra-reactive factor serine protease p100|manan-binding lectin serine protease-1|mannan-binding lectin serine protease 1|mannan-binding lectin serine protease 1 (C4/C2 activating component of Ra-reactive factor)|mannan-binding lectin serine protease 1, isof
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