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LGMN 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00005641-T01
  • Visit Frequency :
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-LGMN full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 47.74
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-LGMN antibody (H00005641-B01) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00005641-T01
    LGMN transfected lysate.
    Western Blot
    QC Testing of H00005641-T01
    Lane 1: LGMN transfected lysate ( 47.74 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 5641
  • Protein Accession#:
  • -
  • Gene Name:
  • LGMN
  • Gene Alias:
  • Gene Description:
  • legumain
  • Gene Summary:
  • This gene encodes a cysteine protease that has a strict specificity for hydrolysis of asparaginyl bonds. This enzyme may be involved in the processing of bacterial peptides and endogenous proteins for MHC class II presentation in the lysosomal/endosomal systems. Enzyme activation is triggered by acidic pH and appears to be autocatalytic. Protein expression occurs after monocytes differentiate into dendritic cells. A fully mature, active enzyme is produced following lipopolysaccharide expression in mature dendritic cells. Overexpression of this gene may be associated with the majority of solid tumor types. This gene has a pseudogene on chromosome 13. Several alternatively spliced transcript variants have been described, but the biological validity of only two has been determined. These two variants encode the same isoform. [provided by RefSeq
  • Other Designations:
  • asparaginyl endopeptidase,cysteine protease 1,protease, cysteine, 1 (legumain)
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