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LGMN (Human) IP-WB Antibody Pair

  • Catalog # : H00005641-PW1
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  • Specification
  • Product Description:
  • This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Immunoprecipitation-Western Blot (IP-WB)

    QC Testing of H00005641-PW1
    Immunoprecipitation of LGMN transfected lysate using rabbit polyclonal anti-LGMN and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-LGMN.
  • Supplied Product:
  • Antibody pair set content:
    1. Antibody pair for IP: rabbit polyclonal anti-LGMN (300 ul)
    2. Antibody pair for WB: mouse purified polyclonal anti-LGMN (50 ug)
  • Storage Instruction:
  • Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
  • Applications
  • Application Image
  • Immunoprecipitation-Western Blot
  • Gene Information
  • Entrez GeneID:
  • 5641
  • Gene Name:
  • LGMN
  • Gene Alias:
  • Gene Description:
  • legumain
  • Gene Summary:
  • This gene encodes a cysteine protease that has a strict specificity for hydrolysis of asparaginyl bonds. This enzyme may be involved in the processing of bacterial peptides and endogenous proteins for MHC class II presentation in the lysosomal/endosomal systems. Enzyme activation is triggered by acidic pH and appears to be autocatalytic. Protein expression occurs after monocytes differentiate into dendritic cells. A fully mature, active enzyme is produced following lipopolysaccharide expression in mature dendritic cells. Overexpression of this gene may be associated with the majority of solid tumor types. This gene has a pseudogene on chromosome 13. Several alternatively spliced transcript variants have been described, but the biological validity of only two has been determined. These two variants encode the same isoform. [provided by RefSeq
  • Other Designations:
  • asparaginyl endopeptidase,cysteine protease 1,protease, cysteine, 1 (legumain)
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