PRPS2 polyclonal antibody (A01)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant PRPS2.
Immunogen
PRPS2 (NP_002756, 160 a.a. ~ 269 a.a) partial recombinant protein with GST tag.
Sequence
AEWKNCIIVSPDAGGAKRVTSIADRLNVEFALIHKERKKANEVDRMVLVGDVKDRVAILVDDMADTCGTICHAADKLLSAGATKVYAILTHGIFSGPAISRINNAAFEAV
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (98); Rat (99)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (38.21 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
PRPS2 polyclonal antibody (A01), Lot # 051212JC01. Western Blot analysis of PRPS2 expression in Daoy.Western Blot (Recombinant protein)
ELISA
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Gene Info — PRPS2
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Interactome
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Pathway
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Publication Reference
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Protein and nucleotide biosynthesis are coupled by a single rate-limiting enzyme, PRPS2, to drive cancer.
John T Cunningham, Melissa V Moreno, Alessia Lodi , Sabrina M Ronen, Davide Ruggero.
Cell 2014 May; 157(5):1088.
Application:WB, Mouse, Mouse primary B lymphocyte, Mouse embryo fibroblasts, NIH3T3 cells.
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Direct role of nucleotide metabolism in C-MYC-dependent proliferation of melanoma cells.
Mannava S, Grachtchouk V, Wheeler LJ, Im M, Zhuang D, Slavina EG, Mathews CK, Shewach DS, Nikiforov MA.
Cell Cycle 2008 Jun; 7(15):2392.
Application:WB-Ce, Human, Normal melanocytes, Melanoma SK-Mel-19, SK-Mel-29, SK-Mel-103 cells.
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Protein and nucleotide biosynthesis are coupled by a single rate-limiting enzyme, PRPS2, to drive cancer.
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