PROX1 monoclonal antibody (M02), clone 1E7
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant PROX1.
Immunogen
PROX1 (NP_002754.2, 638 a.a. ~ 737 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
YARQAINDGVTSTEELSITRDCELYRALNMHYNKANDFEVPERFLEVAQITLREFFNAIIAGKDVDPSWKKAIYKVICKLDSEVPEIFKSPNCLQELLHE
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (100); Rat (40)
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged PROX1 is approximately 1ng/ml as a capture antibody.ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to PROX1 on HeLa cell . [antibody concentration 10 ug/ml] -
Gene Info — PROX1
Entrez GeneID
5629GeneBank Accession#
NM_002763Protein Accession#
NP_002754.2Gene Name
PROX1
Gene Alias
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Gene Description
prospero homeobox 1
Omim ID
601546Gene Ontology
HyperlinkOther Designations
prospero-related homeobox 1
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Interactome
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Disease
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Publication Reference
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Tau reduction affects excitatory and inhibitory neurons differently, reduces excitation/inhibition ratios, and counteracts network hypersynchrony.
Che-Wei Chang, Mark D Evans, Xinxing Yu, Gui-Qiu Yu, Lennart Mucke.
Cell Reports 2021 Oct; 37(3):109855.
Application:IF, Mouse, Mouse primary neuronal cultures.
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Tau reduction affects excitatory and inhibitory neurons differently, reduces excitation/inhibition ratios, and counteracts network hypersynchrony.
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