PROS1 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human PROS1 partial ORF ( NP_000304, 419 a.a. - 516 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
GLLETKVYFAGFPRKVESELIKPINPRLDGCIRSWNLMKQGASGIKEIIQEKQNKHCLVTVEKGSYYPGSGIAQFHIDYNNVSSAEGWHVNVTLNIRP
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.52
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — PROS1
Entrez GeneID
5627GeneBank Accession#
NM_000313Protein Accession#
NP_000304Gene Name
PROS1
Gene Alias
PROS, PS21, PS22, PS23, PS24, PS25, PSA
Gene Description
protein S (alpha)
Omim ID
176880Gene Ontology
HyperlinkGene Summary
This gene encodes a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. It is found in plasma in both a free, functionally active form and also in an inactive form complexed with C4b-binding protein. Mutations in this gene result in autosomal dominant hereditary thrombophilia. An inactive pseudogene of this locus is located at an adjacent region on chromosome 3. [provided by RefSeq
Other Designations
protein S, alpha|protein Sa
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Interactome
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Pathway
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Disease
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