PROS1 monoclonal antibody (M01), clone 3D7
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant PROS1.
Immunogen
PROS1 (NP_000304, 419 a.a. ~ 516 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
GLLETKVYFAGFPRKVESELIKPINPRLDGCIRSWNLMKQGASGIKEIIQEKQNKHCLVTVEKGSYYPGSGIAQFHIDYNNVSSAEGWHVNVTLNIRP
Host
Mouse
Reactivity
Human
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.52 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — PROS1
Entrez GeneID
5627GeneBank Accession#
NM_000313Protein Accession#
NP_000304Gene Name
PROS1
Gene Alias
PROS, PS21, PS22, PS23, PS24, PS25, PSA
Gene Description
protein S (alpha)
Omim ID
176880Gene Ontology
HyperlinkGene Summary
This gene encodes a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. It is found in plasma in both a free, functionally active form and also in an inactive form complexed with C4b-binding protein. Mutations in this gene result in autosomal dominant hereditary thrombophilia. An inactive pseudogene of this locus is located at an adjacent region on chromosome 3. [provided by RefSeq
Other Designations
protein S, alpha|protein Sa
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Interactome
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Pathway
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Disease
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