PROP1 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-PROP1 full-length
Host
Human
Theoretical MW (kDa)
24.97
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-PROP1 antibody (H00005626-B01) by Western Blots.
SDS-PAGE Gel
PROP1 transfected lysate.
Western Blot
Lane 1: PROP1 transfected lysate ( 24.97 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — PROP1
Entrez GeneID
5626GeneBank Accession#
NM_006261.2Protein Accession#
NP_006252.1Gene Name
PROP1
Gene Alias
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Gene Description
PROP paired-like homeobox 1
Omim ID
601538Gene Ontology
HyperlinkGene Summary
PROP1 has both DNA-binding and transcriptional activation ability. Its expression leads to ontogenesis of pituitary gonadotropes, as well as somatotropes, lactotropes, and caudomedial thyrotropes. Inactivating mutations in PROP1 result in deficiencies of luteinizing hormone (LH; MIM 152780), follicle-stimulating hormone (FSH; MIM 136530), growth hormone (GH; MIM 139250), prolactin (PRL; MIM 176760), and thyroid-stimulating hormone (TSH; MIM 188540). See combined pituitary hormone deficiency (CPHD; MIM 262600).[supplied by OMIM
Other Designations
OTTHUMP00000161487|prophet of Pit1, paired-like homeodomain transcription factor
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Interactome
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Disease
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