PROC (Human) IP-WB Antibody Pair
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of PROC transfected lysate using mouse monoclonal anti-PROC and Protein A Magnetic Bead (U0007), and immunoblotted with rabbit polyclonal anti-PROC.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: mouse monoclonal anti-PROC (300 ug)
2. Antibody pair for WB: rabbit polyclonal anti-PROC (50 ul)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — PROC
Entrez GeneID
5624Gene Name
PROC
Gene Alias
PC, PROC1
Gene Description
protein C (inactivator of coagulation factors Va and VIIIa)
Omim ID
176860Gene Ontology
HyperlinkGene Summary
The PROC gene encodes protein C (EC 3.4.21.69), a vitamin K-dependent plasma glycoprotein that is a key component of the anticoagulant system. Protein C is cleaved to its activated form, 'activated protein C' (APC) on endothelial cells by the thrombin-thrombomodulin complex (MIM 176930; MIM 188040) and then acts as a serine protease to degrade the activated forms of coagulation factors V (F5; MIM 612309) and VIII (F8; see MIM 306700). Protein S (PROS1; MIM 176880), also a vitamin K-dependent plasma protein, functions as a cofactor to activated protein C.[supplied by OMIM
Other Designations
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