DNAJC3 monoclonal antibody (M01), clone 4D3-F2
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More Files
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Immunofluorescence
Immunofluorescence of monoclonal antibody to DNAJC3 on HeLa cell. [antibody concentration 10 ug/ml]
Western Blot detection against Immunogen (51.48 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a full length recombinant DNAJC3.
Immunogen
DNAJC3 (AAH33823, 1 a.a. ~ 234 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MVAPGSVTSRLGSVFPFLLVLVDLQYEGAECGVNADVEKHLELGKKLLAAGQLADALSQFHAAVDGDPDNYIAYYRRATVFLAMGKSKAALPDLTKVIQLKMDFTAARLQRGHLLLKQGKLDEAEDDFKKVVFPVPSLLGLQRSLLDDLYLLFWFFLMKKVTFRCLSSAISECLPQSLNLMKFNLLISFLLLWTVRLVSCLRSIHYAVGSKTFLISSKSFMVLCFIFKPIVYLS
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (95); Rat (93)
Isotype
IgG2a kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (51.48 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to DNAJC3 on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — DNAJC3
Entrez GeneID
5611GeneBank Accession#
BC033823Protein Accession#
AAH33823Gene Name
DNAJC3
Gene Alias
HP58, P58, P58IPK, PRKRI
Gene Description
DnaJ (Hsp40) homolog, subfamily C, member 3
Omim ID
601184Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene contains multiple tetratricopeptide repeat (TPR) motifs as well as the highly conserved J domain found in DNAJ chaperone family members. It is a member of the tetratricopeptide repeat family of proteins and acts as an inhibitor of the interferon-induced, dsRNA-activated protein kinase (PKR). [provided by RefSeq
Other Designations
OTTHUMP00000018567|protein-kinase, interferon-inducible double stranded RNA dependent inhibitor
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Interactome
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Publication Reference
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p58IPK is an inhibitor of the eIF2α kinase GCN2 and its localization and expression underpin protein synthesis and ER processing capacity.
Roobol A, Roobol J, Bastide A, Knight JR, Willis AE, Smales CM.
The Biochemical Journal 2015 Jan; 465(2):213.
Application：WB-Tr, Mouse, CHOK1 cells.
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p58IPK is an inhibitor of the eIF2α kinase GCN2 and its localization and expression underpin protein synthesis and ER processing capacity.
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