Products

Western Blot (Transfected lysate)

Immunofluorescence (Transfected cell)

Flow Cytometry (Transfected cell)

Entrez GeneID

GeneBank Accession#

Protein Accession#

Gene Name

MAP2K6

Gene Alias

MAPKK6, MEK6, MKK6, PRKMK6, SAPKK3

Gene Description

mitogen-activated protein kinase kinase 6

Omim ID

Gene Ontology

Gene Summary

This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis. [provided by RefSeq

Other Designations

protein kinase, mitogen-activated, kinase 6 (MAP kinase kinase 6)