PRKCSH (Human) Recombinant Protein (P02)
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More Files
- More Functions
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Specification
Product Description
Human PRKCSH full-length ORF ( AAH13586.1, 1 a.a. - 398 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MAEVTREGFRLKKILIEDWKKAREEKQKKLIELQAGKKSLEDQVEMLRTVKEEAEKPEREAKEQHQKLWEEQLAAAKAQQEQELAADAFKELDDDMDGTVSVTELQTHPELDTDGDGALSEAEAQALLSGDTQTDATSFYDRVWAAIRDKYRSEALPTDLPTPSAPDLTEPKEEQPPVPSSPTEEEEEEEEEEEEAEEEEEEEDSEEAPPPLSPPQPASPAEEDKMPPYDEQTQAFIDAAQEARNKFEEAERSLKDMEESIRNLEQEISFDFGPNGEFAYLYSQCYELTTNEYVYRLCPFKLVSQKPKLGGSPTSLGTWGSWIGPDHDKFSAMKYEQGTGCWQGPNRSTTVRLLCGKETMVTSTTEPSRCEYLMELMTPAACPEPPPEAPTEDDHDEL
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
71.4
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — PRKCSH
Entrez GeneID
5589GeneBank Accession#
BC013586.1Protein Accession#
AAH13586.1Gene Name
PRKCSH
Gene Alias
AGE-R2, G19P1, PCLD, PLD1
Gene Description
protein kinase C substrate 80K-H
Gene Ontology
HyperlinkGene Summary
This gene encodes the beta-subunit of glucosidase II, an N-linked glycan-processing enzyme in the endoplasmic reticulum (ER). This protein is an acidic phospho-protein known to be a substrate for protein kinase C. Mutations in this gene have been associated with the autosomal dominant polycystic liver disease (PCLD). Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq
Other Designations
AGE-binding receptor 2|glucosidase II, beta subunit|hepatocystin|protein kinase C substrate, 80 Kda protein
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Interactome
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Disease
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Publication Reference
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PRKCSH contributes to tumorigenesis by selective boosting of IRE1 signaling pathway.
Shin GC, Moon SU, Kang HS, Choi HS, Han HD, Kim KH.
Nature Communications 2019 Jul; 10(1):3185.
Application:PI, WB-Re, Recombinant protein.
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PRKCSH contributes to tumorigenesis by selective boosting of IRE1 signaling pathway.
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