PRKD1 polyclonal antibody (A01)
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant PRKD1.
Immunogen
PRKD1 (NP_002733, 314 a.a. ~ 404 a.a) partial recombinant protein with GST tag.
Sequence
PKVPNNCLGEVTINGDLLSPGAESDVVMEEGSDDNDSERNSGLMDDMEEAMVQDAEMAMAECQNDSGEMQDPDPDHEDANRTISPSTSNNI
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (87); Rat (88)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.12 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — PRKD1
Entrez GeneID
5587GeneBank Accession#
NM_002742Protein Accession#
NP_002733Gene Name
PRKD1
Gene Alias
PKC-MU, PKCM, PKD, PRKCM
Gene Description
protein kinase D1
Omim ID
605435Gene Ontology
HyperlinkGene Summary
Members of the protein kinase C (PKC) family function in many extracellular receptor-mediated signal transduction pathways. See PRKCA (MIM 176960) for further background information. The PRKCM gene encodes a cytosolic serine-threonine kinase that binds to the trans-Golgi network and regulates the fission of transport carriers specifically destined to the cell surface.[supplied by OMIM
Other Designations
protein kinase C, mu
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Interactome
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Disease
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Publication Reference
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PKD Phosphorylation as Novel Pathway of KV11.1 Regulation.
Steffensen AB, Bomholtz SH, Andersen MN, Olsen JV, Mutsaers N, Lundegaard PR, Lundby A, Schmitt N.
Cellular Physiology and Biochemistry 2018 Jun; 47(4):1742.
Application:WB-Tr, Human, HEK 293 cells.
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Protein Kinase D1 regulates focal adhesion dynamics and cell adhesion through Phosphatidylinositol-4-phosphate 5-kinase type-l γ.
Durand N, Bastea LI, Long J, Döppler H, Ling K, Storz P.
Scientific Reports 2016 Oct; 6:35963.
Application:IF, Mouse, NIH-3T3, MCF-7 cells.
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Small heat shock protein 20 (Hsp20) facilitates nuclear import of protein kinase D 1 (PKD1) during cardiac hypertrophy.
Sin YY, Martin TP, Wills L, Currie S, Baillie GS.
Cell Communication and Signaling 2015 Mar; 13:16.
Application:IP, WB, Rat, Cardiac myocytes.
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PKD Phosphorylation as Novel Pathway of KV11.1 Regulation.
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