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PKN1 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00005585-T01
  • Visit Frequency :
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-PKN1 full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 103.73
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-PKN1 antibody (H00005585-B01) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00005585-T01
    PKN1 transfected lysate.
    Western Blot
    QC Testing of H00005585-T01
    Lane 1: PKN1 transfected lysate ( 103.73 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 5585
  • Gene Name:
  • PKN1
  • Gene Alias:
  • DBK,MGC46204,PAK1,PKN,PKN-ALPHA,PRK1,PRKCL1
  • Gene Description:
  • protein kinase N1
  • Gene Summary:
  • The protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq
  • Other Designations:
  • protein kinase C-like 1,protein kinase C-like PKN,protein kinase C-related kinase 1,serine-threonine kinase N,serine/threonine protein kinase N
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