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Last updated: 2016/10/23
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PRKAR2A MaxPab mouse polyclonal antibody (B01)MaxPab

  • Catalog # : H00005576-B01
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  • Specification
  • Product Description:
  • Mouse polyclonal antibody raised against a full-length human PRKAR2A protein.
  • Immunogen:
  • PRKAR2A (AAH02763, 1 a.a. ~ 382 a.a) full-length human protein.
  • Sequence:
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Antibody reactive against mammalian transfected lysate.
  • Storage Buffer:
  • No additive
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • For IHC and IF applications, antibody purification with Protein A will be needed prior to use.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • PRKAR2A MaxPab polyclonal antibody. Western Blot analysis of PRKAR2A expression in human colon.
  • PDF DownloadProtocol Download
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western Blot analysis of PRKAR2A expression in transfected 293T cell line (H00005576-T01) by PRKAR2A MaxPab polyclonal antibody.

    Lane1:PRKAR2A transfected lysate(42.02 KDa).
    Lane2:Non-transfected lysate.
  • PDF DownloadProtocol Download
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 5576
  • Gene Name:
  • Gene Alias:
  • MGC3606,PKR2,PRKAR2
  • Gene Description:
  • protein kinase, cAMP-dependent, regulatory, type II, alpha
  • Gene Summary:
  • cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This subunit can be phosphorylated by the activated catalytic subunit. It may interact with various A-kinase anchoring proteins and determine the subcellular localization of cAMP-dependent protein kinase. This subunit has been shown to regulate protein transport from endosomes to the Golgi apparatus and further to the endoplasmic reticulum (ER). [provided by RefSeq
  • Other Designations:
  • cAMP-dependent protein kinase regulatory subunit RII alpha,cAMP-dependent protein kinase, regulatory subunit alpha 2,protein kinase A, RII-alpha subunit
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