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PRG2 rabbit monoclonal antibody

  • Catalog # : H00005553-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human PRG2 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human PRG2 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human PRG2 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 5553
  • GeneBank Accession#:
  • PRG2
  • Gene Name:
  • PRG2
  • Gene Alias:
  • BMPG,MBP,MBP1,MGC14537
  • Gene Description:
  • proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
  • Gene Summary:
  • The protein encoded by this gene is the predominant constituent of the crystalline core of the eosinophil granule. High levels of the proform of this protein are also present in placenta and pregnancy serum, where it exists as a complex with several other proteins including pregnancy-associated plasma protein A (PAPPA), angiotensinogen (AGT), and C3dg. This protein may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin, and in immune hypersensitivity reactions. It is directly implicated in epithelial cell damage, exfoliation, and bronchospasm in allergic diseases. [provided by RefSeq
  • Other Designations:
  • bone-marrow proteoglycan,eosinophil granule major basic protein,eosinophil major basic protein,natural killer cell activator,proteoglycan 2,proteoglycan 2 preproprotein
  • Gene Pathway
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