SRGN rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human SRGN peptide using ARM Technology.
Immunogen
A synthetic peptide of human SRGN is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human SRGN peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — SRGN
Entrez GeneID
5552GeneBank Accession#
SRGNGene Name
SRGN
Gene Alias
FLJ12930, MGC9289, PPG, PRG, PRG1
Gene Description
serglycin
Omim ID
177040Gene Ontology
HyperlinkGene Summary
This gene encodes a protein best known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of many hematopoietic cells also contain a protease-resistant peptide core, which may be important for neutralizing hydrolytic enzymes. This encoded protein was found to be associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis. [provided by RefSeq
Other Designations
OTTHUMP00000019716|hematopoetic proteoglycan core peptide|platelet proteoglycan protein core|proteoglycan 1, secretory granule|proteoglycan protein core for mast cell secretory granule|secretory granule proteoglycan 1|secretory granule proteoglycan core p
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Interactome
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Toll Free : +1-877-853-6098 - +1-909-992-3401
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