PRELP purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Western Blot (Tissue lysate)
PRELP MaxPab polyclonal antibody. Western Blot analysis of PRELP expression in human spleen.
Western Blot (Transfected lysate)
Western Blot analysis of PRELP expression in transfected 293T cell line (H00005549-T02) by PRELP MaxPab polyclonal antibody.
Lane 1: PRELP transfected lysate(42.02 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human PRELP protein.
Immunogen
PRELP (NP_002716.1, 1 a.a. ~ 382 a.a) full-length human protein.
Sequence
MRSPLCWLLPLLILASVAQGQPTRRPRPGTGPGRRPRPRPRPTPSFPQPDEPAEPTDLPPPLPPGPPSIFPDCPRECYCPPDFPSALYCDSRNLRKVPVIPPRIHYLYLQNNFITELPVESFQNATGLRWINLDNNRIRKIDQRVLEKLPGLVFLYMEKNQLEEVPSALPRNLEQLRLSQNHISRIPPGVFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKNLMQLNLAHNILRKMPPRVPTAIHQLYLDSNKIETIPNGYFKSFPNLAFIRLNYNKLTDRGLPKNSFNISNLLVLHLSHNRISSVPAINNRLEHLYLNNNSIEKINGTQICPNDLVAFHDFSSDLENVPHLRYLRLDGNYLKPPIPLDLMMCFRLLQSVVI
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (89); Rat (89)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
PRELP MaxPab polyclonal antibody. Western Blot analysis of PRELP expression in human spleen.Western Blot (Transfected lysate)
Western Blot analysis of PRELP expression in transfected 293T cell line (H00005549-T02) by PRELP MaxPab polyclonal antibody.
Lane 1: PRELP transfected lysate(42.02 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — PRELP
Entrez GeneID
5549GeneBank Accession#
NM_002725Protein Accession#
NP_002716.1Gene Name
PRELP
Gene Alias
MGC45323, MST161, MSTP161, SLRR2A
Gene Description
proline/arginine-rich end leucine-rich repeat protein
Omim ID
601914Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq
Other Designations
55 kDa leucine-rich repeat protein of articular cartilage|OTTHUMP00000034099|prolargin proteoglycan|proline arginine-rich end leucine-rich repeat protein
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Interactome
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Disease
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