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PRCP 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00005547-T02
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-PRCP full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 55.8
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-PRCP antibody (H00005547-B01P) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00005547-T02
    PRCP transfected lysate.
    Western Blot
    QC Testing of H00005547-T02
    Lane 1: PRCP transfected lysate ( 55.80 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 5547
  • Gene Name:
  • PRCP
  • Gene Alias:
  • Gene Description:
  • prolylcarboxypeptidase (angiotensinase C)
  • Gene Summary:
  • The protein encoded by this gene is a lysosomal prolylcarboxypeptidase, which cleaves C-terminal amino acids linked to proline in peptides such as angiotension II, III and des-Arg9-bradykinin. The cleavage occurs at acidic pH, but the enzyme activity is retained with some substrates at neutral pH. This enzyme has been shown to be an activator of the cell matrix-associated prekallikrein. The importance of angiotension II, one of the substrates of this enzyme, in regulating blood pressure and electrolyte balance suggests that this gene may be related to essential hypertension. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq
  • Other Designations:
  • angiotensinase C,lysosomal Pro-x carboxypeptidase,lysosomal carboxypeptidase C,proline carboxypeptidase,prolylcarboxypeptidase,prolylcarboxypeptidase isoform 1 preproprotein
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